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Role of E-cadherin Expression in Breast Carcinoma

  • By AN Dhanya, B Niranjana Murthy
  • Original Article
  • April-June 2018

Cancer of breast has emerged as the leading site of cancer in India. E-cadherin (E-CD) is one of calciumdependent transmembrane glycoprotein mediating cell–cell adhesion. It has its application in differentiating invasive ductal carcinoma not otherwise specified (IDC-NOS) vs invasive lobular carcinomas (ILCs) and predicting the aggressiveness of the tumor. In this study, we intend to see E-CD expression in breast carcinoma by immunohistochemistry (IHC), comparing its status with histological grade and type.

 

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