Histomorphologoical Spectrum of Neoplasma in the Nasal Cavity and paranasal sinuses in a tertiary care hospital

  • By Dr. Sharmila P.S, Dr. Jyothi A Raj, Dr. Mitika Shrivastava, Dr. Mahantachar V, Dr. T Rajaram
  • Original Article

Introduction : Nasal cavity and paranasal sinuses present a spectrum of neoplasms, with clinical manifestations similar to non- neoplastic lesions. Histopathological examination is the mainstay in the diagnosis and management of these neoplasms.

Objective : To study the morphology of neoplasms in the sino-nasal region and their incidence in relation to clinical presentation, age and sex.

Methods : Biopsies from all neoplasms in the nasal cavity and paranasal sinuses, over a period of three years, were retrospectively retrieved and classified based on histology. These findings were correlated with clinical features.

Results: in three years, 20 neoplasma were reported, accounting for 0.15% of all surgical specimens. 11 of them were epithelial neoplasms (55%) and 9 were non-epithelial (45%). Benign tumors (60%) were more common than malignant tumors (40%). Angiofibroma was the commonest benign neoplasm (50%). Squamous cell carcinoma was the commonest malignant neoplasm. The youngest patient was twelve and the oldest was seventy-five years of age. There was a slight male predominance. Rare lesions included metastatic renal cell carcinoma, ameloblastoma and rhabdomyosarcoma.

Conclusion : Neoplasms are uncommon in the nasal cavity and paranasal sinuses, with clinical features similar to non-neoplstic lesions. Categorization based on histopathological features helps in their differential diagnosis, management and prognosis.


Request For The Full Article...

* indicates required field
Article Details
Personal Details